ATROPINE-FUNCTIONALIZED GOLD NANOPARTICLES BINDING TO MUSCARINIC RECEPTORS AFTER PASSAGE ACROSS THE INTESTINAL EPITHELIUM

Atropine-functionalized gold nanoparticles binding to muscarinic receptors after passage across the intestinal epithelium

Gold nanoparticles have a high potential to be a treatment of diseases by their specific drug delivery properties and multivalent receptor stimulation.For the present project, spherical gold nanoparticles were synthesized and functionalized with the muscarinic receptor antagonist atropine (Au-MUDA-AT NPs).The diameter of the gold core could precise

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Measurement properties of the Dutch–Flemish patient-reported outcomes measurement information system (PROMIS) physical function item bank and instruments: a systematic review

Abstract Background Limitations in physical functioning are a big concern especially for patients with chronic Book or musculoskeletal diseases.Therefore, physical functioning is often used as a core outcome of treatments.The generic patient-reported outcomes information system (PROMIS) physical function (PF) item bank has shown potential to measur

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Tokamak divertor plasma emulation with machine learning

Future tokamak devices that aim to create conditions relevant to power plant operations must consider strategies for mitigating damage to plasma facing components in the divertor.One of the goals of MAST-U tokamak operations is to inform these considerations by researching advanced divertor configurations that aid stable plasma detachment.Machine d

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Do North Korean Social Media Show Signs of Change?: An Examination of a YouTube Channel Using Qualitative Tagging and Social Network Analysis

This study examines the interplay between the reactions of YouTube users and North Korean propaganda.Interesting enough, the study has noticed changes in the strict media environment under young leader Kim.Messages delivered by the communist regime to the outside world appeared to resemble those of ‘normal’ countries.Although North Korean YouTu

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